Chii chinonzi QuickMice™?
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QuickMice ™ inoreva mbeva dzinogadzirwa neTurboMice ™tekinoroji, kusanganisira ese ari maviri mbeva dzakaitwa nevanhu uye mamwe akajairika gene-akagadziriswa mbeva, akadai seKnocked-In (KI), Knocked-Out (KO), uye Conditional Knocked-out (CKO) mbeva.Uyezve, neTurboMice ™Tekinoroji, yedu inokwikwidza zvakanyanya QuickMice ™ sevhisi inogona kupa marefu chidimbu-akagadziridzwa mbeva, akawanda-locus gene-yakagadziriswa mbeva, batch kugadzira mbeva, yakakwirira-kukosha mbeva, nezvimwe.
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QuickMice™ inokurumidza homozygous mbeva kugadzirisa
Sero inonzi ihomozygous yerimwe gene kana maalleles akafanana ejini aripo pamakromosomes ehomologous.
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QuickMice ™ inokurumidza gene-edited humanized mouse customization
Mhando dzembeva dzakagadzirwa nevanhu dzine huwandu hwakasiyana hwekushandisa munzvimbo dzekutsvagisa dzeAIDS, gomarara, chirwere chinotapukira, uye chirwere cheropa.
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QuickMice™ inokurumidza KI mbeva kugadzirisa
Knock-in (KI) inzira inoshandisa homologous recombination yemajini kuendesa exogenous inoshanda geni mune homologous kutevedzana musero uye genome, uye kuwana kutaura zvakanaka musero mushure mekuita gene recombination.
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QuickMice™ inokurumidza CKO mbeva kugadzirisa
Conditional Knock-out (CKO) itishu-chaiyo gene kugogodza tekinoroji inowanikwa neyakagadziriswa recombination system.
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QuickMice™ yakawanda-locus gene-yakagadziriswa mbeva kugadzirisa
NokushandisaTurboMice™tekinoroji, tinokwanisa kutarisisa zvakananga embryonic stem masero mushure mekugadzirisa majini mumazuva 3-5, tobva tagadzira tetraploid sero, uye towana homozygous multi-locus gene-edited mbeva mumwedzi 3-5 mushure mekuberekerwa naamai mbeva, izvo zvinogona kuchengetedza 1 gore. kune vatengi vedu.
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QuickMice™ chimedu chakareba gene-yakagadziriswa mbeva
TurboMice™tekinoroji inogonesa kurongeka kwemajini ezvimedu zvirefu pamusoro pe20kb, nokudaro zvichifambisa kukurumidza kugadzirwa kwemhando dzakaomarara senge humanization, conditional knockout (CKO), uye hombe fragment knock-in (KI).
Kuyerera Kwebasa
