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Quickmice™ Fast KI Mouse Kugadzirisa

quickmice-fast-ki-mouse-customization-chigadzirwa

Knock-in (Knock-in, KI) inzira inoshandisa homologous recombination yemajini kuendesa exogenous inoshanda geni mune homologous kutevedzana musero uye genome, uye kuwana kutaura zvakanaka muchitokisi mushure mekubatanidzwazve kwejeni.

Zvinotora 5-6 mwedzi kuwana Neo-delete heterozygous mbeva uye yakazara 10-12 mwedzi kuvaka KI homozygous mbeva modhi ine yakaderera budiriro mazinga uchishandisa echinyakare hunyanzvi, nekuti hunyanzvi uhu hune low chimera positivity uye hunoda kusangana negonzo tora Neo-deteted heterozygous mbeva, uyezve kupfuya akaberekwa heterozygous mbeva kwe 2-3 zvizvarwa kuwana homozygous KI mbeva.

Chizvarwa Chitsva cheRapid Mouse Preparation Technology

TurboMice™

Tinogona kukurumidza kukupa KI homozygous mbeva modhi nekushandisa TurboMice™ tekinoroji kuvandudza mwero webudiriro.

Zvichienderana nechirongwa chekugadzirisa majini nemasayendisiti edu, tinokwanisa kupedzisa kuongorora kweakagadziridzwa embryonic stem cells mukati memazuva matatu kusvika mashanu, tobva tagadzira tetraploid embryo.Mushure mekuberekwa kwaamai, homozygous humanized mice inogona kuwanikwa mukati memwedzi 2-4, iyo inogona kuchengetedza 7-8 mwedzi kune vatengi.

Zvemukati zveSevhisi

Service Nha. Technical indexes Delivery content Delivery cycle
MC002-1 kureba kwejini rimwe chete <5kb 3-9 KI homozygous mbeva dzevarume 2-4 mwedzi
MC002-2 kureba kwejini rimwe chete <5kb 10-19 KI homozygous male mbeva 2-4 mwedzi
MC002-3 kureba kwejini rimwe chete <5kb 20 KI homozygous male mbeva 3-5 mwedzi
MC002-4 kureba kwejini rimwe chete 5kb-10kb 3-9 KI homozygous mbeva dzevarume 3-4 mwedzi
MC002-5 kureba kwejini rimwe chete 5kb-10kb 10-19 KI homozygous male mbeva 3-4 mwedzi
MC002-6 kureba kwejini rimwe chete 5kb-10kb 20 KI homozygous male mbeva 3-5 mwedzi

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